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CAS 5785-2 Testosterone Propionate An API For The Treatment Of Male Testosterone

CAS 5785-2 Testosterone Propionate An API For The Treatment Of Male Testosterone

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    5785-2 Testosterone Propionate

    ,

    API Testosterone Propionate

    ,

    5785-2 Male Testosterone

  • Product Title
    Testosterone Propionate
  • Brand Name
    Kan Ying
  • Purity
    99%
  • Color
    White Granules Or Powder
  • CAS No
    57-85-2
  • Shelf Life
    2 Years
  • Storage
    Cool Dry Place
  • Place of Origin
    India
  • Brand Name
    Kan Ying
  • Minimum Order Quantity
    1kg
  • Price
    To discuss
  • Packaging Details
    1kg-25kg
  • Delivery Time
    2
  • Payment Terms
    L/C, D/A, D/P, T/T, Western Union, MoneyGram,Dollars
  • Supply Ability
    200000

CAS 5785-2 Testosterone Propionate An API For The Treatment Of Male Testosterone

 

Testosterone Propionate (CAS5785-2), An API For The Treatment Of Male Testosterone

 

1. Product title: Testosterone propionate

 

2. Product parameter table:

The density of 1.1 + / - 0.1 g/cm3
Boiling point 454.6±45.0 °C at 760 mmHg
The melting point of 118-123 ° C
Molecular formula C22H32O3
The molecular weight of 344.488
Flash point 196.3 + / - 28.8 ° C
Accurate quality 344.235138
PSA 43.37000
LogP 4.90
Appearance white to grey white crystalline powder
Vapor pressure 0.0± 1.1mmHg at 25°C
The refractive index of 1.538
Storage conditions
This product should be sealed in a cool and dry place.

Water solubility ethanol: 10 mg/mL | & lt; 0.1 g/100 mL at 24.5 ºC
The molecular structure
V. Data of molecular properties:

1. Molar refractive index: 97.32

2. Molar volume (m3/mol) : 311.2

3, equal tension specific capacity (90.2k) : 792.3

4. Surface tension (DYNE /cm) : 42.0

5. Polarization (10-24cm 3) : 38.58

Computational chemistry
1. Reference value of hydrophobic parameter calculation (XlogP) : None

2. Number of hydrogen bond donors :0

3. Number of hydrogen bond receptors :3

4. Number of rotatable bonds :3

5. Tautomeric number :5

6. Polar surface area of topological molecules is 43.4

7. Number of heavy atoms :25

8. Surface charge :0

9. Complexity :621

10. Isotope atomic number :0

11. Determine the number of primary structural centers :6

12. Number of uncertain atomic centers :0

13. Determine the number of chemical bond centers :0

14. Number of uncertain chemical bond centers :0

15. Number of covalent bond units :1

3. Use of testosterone propionate:


An intriguing propionate is a slower-releasing anabolic steroid used primarily to treat low Testosterone levels in men.
Testosterone propionate
The effect is the same as that of testosterone and methyltestosterone, but the duration of intramuscular injection is longer, and it can be injected once every 2-3 days. Clinical for no testosterone, cryptorchidism, male hypogonadism; Gynecological diseases such as menorrhagia, uterine fibroids; Senile osteoporosis and aplastic anemia. Action by stimulating the kidneys to secrete erythropoietin, or by directly stimulating the bone marrow. Androgen replacement therapy for primary hypoorchiasis; Sexual organs are stunted.
Large doses can cause female masculinity, edema, liver damage, jaundice, dizziness and so on. Those who have allergic reaction should stop taking medicine immediately. Contraindicated in patients with liver and renal insufficiency, prostate cancer and pregnant women. If there is crystallization precipitation of injection, it can be injected after heating and dissolving. Puberty delay and dwarfism; Various chronic wasting diseases, etc. The product is transformed into 5α dihydrotestosterone (5α-dihyrotesterone) in vivo, and then binds to cell receptor, enters the nucleus, interacts with chromatin, activates RNA polymerase, promotes protein synthesis and cell metabolism. In addition, testosterone propionate stimulates erythropoietin production and differentiation. Although this product can be absorbed orally, it will be destroyed quickly and invalid in the liver, so intramuscular injection is generally used. After intramuscular injection of testosterone propionate, absorption is slow, with a duration of 2 to 4 days. In blood, 98% of testosterone is bound to sex hormone globulin and only 2% is free form. The half-life is 10-20 minutes. After the inactivation of testosterone in the liver, the metabolites are androsterone isoandrosterone and procholanolone. 90% of them are excreted in urine in combination with uronic and sulfuric acids. About 6% of the unbound form of the product is excreted by bile, a small portion of

which can still be reabsorbed to form the enterohepatic circulation.

CAS 5785-2 Testosterone Propionate An API For The Treatment Of Male Testosterone 0

4. Amount of usage


Intramuscular injection: usually 25mg once, 2-3 times a week. Androgen deficiency: intramuscular injection 10 ~ 50mg once, 2 ~ 3 times a week. Menorrhagia or uterine fibroids: intramuscular injection of 25 ~ 50mg, twice a week. Functional uterine bleeding, combined with progestin: intramuscular injection of 25 ~ 50mg, once every other day, a total of 3 ~ 4 times. Aplastic anemia: 100mg intramuscular injection once daily or every other day for more than 6 months. Senile osteoporosis: intramuscular injection of 25mg 2 ~ 3 times a week for 3 ~ 6 months.

Female breast cancer and breast cancer bone metastasis: intramuscular injection of 50 ~ 100mg, once every other day, 2 ~ 3 months. Large doses can cause female masculinity, edema, liver damage, jaundice, dizziness and so on. Those who have allergic reaction should stop taking medicine immediately. Liver, renal insufficiency, prostate cancer patients and pregnant women should not use. If there is crystallization precipitation of injection, it can be injected after heating and dissolving. Pregnant and breastfeeding women, prostate cancer patients contraindicated; The liver function should be checked regularly in the process of medication, and the drug should be reduced or stopped if there is liver damage. The dosage should be reduced in preadolescent children, and bone age should be measured once every 6 months. Injection: 10mg (1ml), 25mg (1ml), 50mg (1ml) each.

 

5. Adverse reactions


The 17-α -alkyl substituted testosterone is toxic to the liver and can cause jaundice. Long-term use in female patients may cause acne, hirsutism, coarse voice, altered libido and other masculine manifestations. The drug should be discontinued immediately when liver dysfunction and masculinity in women are detected. Large doses can cause female masculinity, edema, liver damage, jaundice, dizziness and so on.

Those who have allergic reaction should stop taking medicine immediately. Liver, renal insufficiency, prostate cancer patients and pregnant women should not use. If there is crystallization precipitation of injection, it can be injected after heating and dissolving. Pregnant and breastfeeding women, prostate cancer patients contraindicated; The liver function should be checked regularly in the process of medication, and the drug should be reduced or stopped if there is liver damage. The dosage should be reduced in preadolescent children, and bone age should be measured once every 6 months.

 
6. Pictures of the product:
 
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