Health Care Raw Materials Tadalafil API 99 Content Joint Venture Spot

Tadalafil API Tadalafil 99 Content Health Care Raw Materials Joint Venture Manufacturer Spot Tadalafil API

1, Product title: Cialis

Chinese synonyms: Tadanafil; Taddenafil; Cialis. (6 r - 12 ar) - 6 - (1, 3 - benzene and two evil MAO - 5 - base) - 2 - methyl - 2,3,6,7,12,12 a - 6 hydrogenated pyrazine and [1 ', 2 '- 1, 6] - [3, 4 - b] pyridine and indole - 1, 4-2 ketone; Tadanafil (standard); (6 r - 12 ar) - 6 - (shigeru benzene and 1, 3-2-5 - base) - 2 - methyl - 2,3,6,7,12,12 A - 6 hydrogenated pyrazine and [1 ', 2 '- 1, 6] - [3, 4 - B] pyridine and indole - 1, 4-2 ketone; Tardanafil (Cialis); Cialis, Cialis

English name :Calais

English synonyms :TADALAFIL; CIALIS; IC 351; (6 r, 12 ar) - 6 - (1, 3 - benzodioxol - 5 - yl) - 2,3,6,7,12,12 a - hexahydro - 2 - methyl - pyrazino [1 ', 2 ': 1, 6] pyrido [3, 4 - b] indole - 1, 4 - dione. TADALAFIL(CIALIS); Taladafil (cialis); Cialis/taladafil; Cialis(IC351)

Molecular formula: C22H19N3O4

Molecular weight: 389.4

CAS no. : 171596-29-5

Physical and chemical properties: white powder, odorless, tasteless, insoluble in water and alcohol.

Tadanafil melting point :302.0℃-303.0℃

Dry weight loss: ≤0.5%

Tadana non heavy metal: ≤50ppm

Content: 99.5% or higher

Specific curl :[a] 20 D=+70-72o (C=1.00, CHCl 3)

TLC: Only one spot

Calais Use: Treatment of male erectile dysfunction. Sexual stimulation is required for this product to take effect. Tadalafil should not be used on women.

2.Calais Pharmacological properties:
The principle of action is the same as sildenafil and vardenafil. Both rely on PDE-5 to improve the vascular dilation of NO by inhibiting the decomposition of cGMP, so that ED patients regain the ability of penile erection, and after taking tadanafil, it is absorbed by the intestines and stomach.

3.Calais Effect of efficacy:
The mean onset time of tadanafil is 16-30 min. The plasma concentration reaches its peak 2-8 h after administration with a half-life of 44-112 h. The half-life is extended with renal insufficiency and the concentration of tadanafil can still be measured in plasma even after 5 days. Clinical reports showed an 83% response rate after taking Cialis, with a reported dosage of 10-20 mg. Its advantage is the side effect is small, lasting for a long time, can have obvious effect in two or three days.

4.Calais Usage.:
The recommended dose of tadanafil is 10mg, to be taken before sex and not affected by eating. If 10mg is not effective, 20mg can be taken at least 30 minutes before sex, with a maximum frequency of once a day. It is best not to take tadalafil continuously daily. It is best to use it on an empty stomach. Do not drink alcohol, strong tea or spicy food before use (the effect is significant only when the user uses it under the state of sexual stimulation).

5.Calais Adverse reactions:
Some users will have adverse reactions, generally dry mouth (sex hunger), back muscle pain, muscle weakness, headache, facial flushing, accelerated heart rate, excessive will lead to frequent headache, excessive spirit, no drowsiness.

6.Calais taboo:
Patients with hypertension, heart disease, diabetes, anemia and renal insufficiency are prohibited. Long-term use may cause drug dependence, avoid compatibility with alkaline drugs.

7.Calais picture: