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Cas 51-55-8 Atropine Sulfate Powder Belladonna Extract Atropine Raw Material

Cas 51-55-8 Atropine Sulfate Powder Belladonna Extract Atropine Raw Material

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    51-55-8 Atropine Sulfate Powder


    51-55-8 Belladonna Extract


    Belladonna Atropine Sulfate Powder

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Cas 51-55-8 Atropine Sulfate Powder Belladonna Extract Atropine Raw Material

High Quality Atropine Sulfate Powder Belladonna Extract Supply Atropine Raw Material Cas51-55-8


1. Product name: Atropine



Atropine is mainly used to treat some nerve agent or pesticide poisoning, symptoms such as slow heart rate, and to reduce the production of saliva during surgery


2.oxazepine parameters:


Product name Atropine
CAS 51-55-8
Density of 1.2±0.1 g/cm3
Boiling point 429.8±45.0 °C at 760 mmHg
Melting point 115-118 °C
Molecular formula C17H23NO3
Molecular weight 289.369
Flash point 213.7±28.7 °C
Precise quality 289.167786
PSA 49.77000
LogP 1.53
Appearance powder
Vapor pressure 0.0±1.1 mmHg at 25°C
Refractive index 1.581
Storage conditions Seal with argon at 0 ℃, dry and keep away from light.
Stability of

Stable at room temperature and pressure

Avoid light, open fire, and high heat


Water solubility H2O: 2 mg/mL
Molecular structure

1, molar refractive index: 80.78

2. Molar volume (CM3 /mol) : 242.4

3, equal tension specific capacity (90.2K) : 646.1

4. Surface tension (DYNE /cm) : 50.4

5, polarization (10-24cm3) : 32.02


Cas 51-55-8 Atropine Sulfate Powder Belladonna Extract Atropine Raw Material 0

3. Atropine Description:


Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.It is typically given intravenously or by injection into a muscle.Eye drops are also available which are used to treat uveitis and amblyopia.The intravenous solution usually begins working within a minute and lasts half an hour to an hour.Large doses may be required to treat poisonings.


4.Atropine Application:


(1) relaxation smooth muscle: This product has a lot of relaxation of the role of visceral smooth muscle, excessive activity or in the spasm of the smooth muscle was a significant relaxation, and the impact of normal activities of the smooth muscle less.
(2) inhibition of gland secretion: by blocking the M - cholinergic receptor inhibition of gland secretion. On the salivary glands and sweat glands of the most obvious inhibition. But also can lacrimal gland and respiratory gland secretion greatly reduced, but the impact of gastric acid secretion is smaller.
(3) the role of the eye: atropine by blocking the pupil sphincter and ciliary muscle M-choline receptors and the performance of mydriasis, increased intraocular pressure and paralysis. These three effects have important clinical significance.
(4) the role of cardiovascular: a larger dose (1 ~ 2mg) atropine can lift the vagus nerve inhibition of the heart, thus making heart rate. Large doses can expand the skin and visceral blood vessels, relieve small arterial spasm. The mechanism of dilation of blood vessels and the lifting of small vasospasm is unknown.
(5) excitement of the central nervous system: high doses of irritability, more words and delirium and so on. Poisoning dose (more than 10mg) can produce hallucinations, orientation disorders, involuntary movement and convulsions and so on.

Cas 51-55-8 Atropine Sulfate Powder Belladonna Extract Atropine Raw Material 1

5. Atropine Matters needing attention:

Not suitable for patients with bronchial asthma. Intravenous atropine in pregnant women can cause fetal tachycardia. This product can secrete into milk and inhibit lactation. Infants and young children are very sensitive to the toxic reaction of this product, especially children with spasmodic paralysis and brain damage. The reaction is stronger. When the ambient temperature is higher, there is a risk of sudden rise in body temperature due to diaphoresis.


Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ophthalmic examination. In refractive and accommodative amblyopia, when occlusion is not appropriate sometimes atropine is given to induce blur in the good eye. Atropine eye drops have been shown to be effective in slowing the progression of myopia in children in several studies, but it is not available for this use, and side effects would limit its use.


Injections of atropine are used in the treatment of bradycardia (a heart rate < 60 beats per minute). Atropine was previously included in international resuscitation guidelines for use in cardiac arrest associated with asystole and PEA, but was removed from these guidelines in 2010 due to a lack of evidence for its effectiveness.[13] For symptomatic bradycardia, the usual dosage is 0.5 to 1 mg IV push, may repeat every 3 to 5 minutes up to a total dose of 3 mg (maximum 0.04 mg/kg). Atropine is also useful in treating second-degree heart block Mobitz Type 1 (Wenckebach block), and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm. It is usually not effective in second-degree heart block Mobitz type 2, and in third-degree heart block with a low Purkinje or ventricular escape rhythm. Atropine has also been used in an effort to prevent a low heart rate during intubation of children; however, evidence dose not support this use.


6. Atropine contraindication:

Glaucoma and prostatic hypertrophy patients, high fever is prohibited.
Note: The above content is only for introduction, the use of drugs must be carried out in regular hospitals under the guidance of doctors