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Minoxidil Oral Hypoglycemic Agents CAS 38304-91-5 High Blood Pressure And Hair Loss

Minoxidil Oral Hypoglycemic Agents CAS 38304-91-5 High Blood Pressure And Hair Loss

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    Minoxidil Oral Hypoglycemic Agents

    ,

    38304-91 Oral Hypoglycemic Agents

    ,

    38304-91 38304-91 oral minoxidil hair loss

  • Product Name
    Minoxidil
  • CAS No
    38304-91-5
  • The Molecular Weight
    209.248
  • Boiling Point
    351.7±45.0 °C At 760 MmHg
  • Molecular Formula
    C9H15N5O
  • Density
    1.5±0.1 G/cm3
  • Point Of Flammability
    166.5±28.7 °C
  • Melting Point
    272-274 °C (dec.)(lit.)
  • Storage
    Cool Dry Place
  • Shelf Life
    2 Years
  • Place of Origin
    India
  • Brand Name
    Kan Ying
  • Minimum Order Quantity
    1KG
  • Price
    To discuss
  • Packaging Details
    1KG/25KG
  • Delivery Time
    2
  • Payment Terms
    L/C, D/A, D/P, T/T, Western Union, MoneyGram,Dollars
  • Supply Ability
    2000000

Minoxidil Oral Hypoglycemic Agents CAS 38304-91-5 High Blood Pressure And Hair Loss

Minoxidil Oral Hypoglycemic Agents CAS 38304-91-5 High Blood Pressure And Hair Loss

 

1,Product title:Minoxidil

 

2, Product parameter table:

 

Product Name Minoxidil
CAS No 38304-91-5
The molecular weight 209.248
Molecular formula C9H15N5O
density 1.5±0.1 g/cm3
boiling point 351.7±45.0 °C at 760 mmHg
melting point 272-274 °C (dec.)(lit.)
point of flammability 166.5±28.7 °C

 

3, Minoxidil Description:

 

Minoxidil, chemically known as 6-(1-piperidyl)-2, 4-pyrimidine diamine-3-oxide, is an organic substance that occurs as a white or whitish crystalline powder. Clinically, as a potassium channel opening agent, it can directly relax the vascular smooth muscle, have a powerful effect of arteriole dilation, reduce peripheral resistance and blood pressure, but has no effect on volume vessels, so it can promote venous reflux. At the same time, cardiac output and heart rate can be increased due to reflex regulation and positive frequency effect, but does not cause postural hypotension.

 

4,Minoxidil use

 

Antihypertensive drugs used in refractory, primary, or renal hypertension. Used to prevent grease alopecia and animal husbandry

 

 

5, Pharmacology and toxicology:

 

Minoxidil directly dilates small arteries and thus depresses blood pressure, but the exact mechanism is unclear. This product does not dilate venules. Reduced peripheral vascular resistance leads to increased reflexive heart rate and cardiac output. Renin activity increased after hypotension, resulting in water and sodium retention. This product does not interfere with vascular motor reflex, so does not occur orthostatic hypotension.

 

6,indications:

 

Severe or refractory hypertension and renal hypertension, its antihypertensive effect is stronger than hydrazine benzidazine. Did not cause postural hypotension, long-term medication did not reduce the efficacy. It has synergistic effect with propranolol and can offset each other's adverse reactions. Topical application in men with cicatricial alopecia (alopecia areata).

Minoxidil Oral Hypoglycemic Agents CAS 38304-91-5 High Blood Pressure And Hair Loss 0

7, Taboo:

 

This product should be used with caution in the following cases: cerebrovascular disease, heart failure not caused by hypertension, coronary heart disease, angina pectoris, myocardial infarction, pericardial effusion, pheochromocytoma, renal dysfunction.

 

8, Matters needing attention:

 

1. After treatment with this product, blood urea nitrogen and creatinine increased at the initial stage, but decreased to the pre-treatment level after continued treatment.

2. Plasma renin activity, serum alkaline phosphatase and blood sodium may be increased.

3. Blood count and hemoglobin may be decreased due to hemodilution.

4. Blood pressure and body weight should be measured regularly when using this product.

5. Sudden withdrawal of medication can cause blood pressure rebound, so it is advisable to withdraw medication gradually.

Medication for pregnant and lactating women:

This product can pass through the placenta, human studies are not enough, in rats and rabbits have a stillbirth effect. Therefore, pregnant women should use with caution. Can be discharged into milk, but no effect on infants has been reported. No data have been reported on lactating women.

Medication for children:

Safety studies in children are lacking.

Medication for the elderly:

The elderly are sensitive to antihypertensive effect, and renal function is often poor, the application of this product should be reduced dose.

 

9, Application:

 

Minoxidil belongs to a class of drugs known as vasodilators. It is not known how minoxidil causes hair growth. This medication is not used for sudden/patchy hair loss, unexplained hair loss (e.g., no family history of hair loss), or hair loss after giving birth.

Minoxidil, applied topically, is widely used for the treatment of hair loss. It is effective in helping promote hair growth in both men and women with androgenic alopecia. About 40% of men experience hair regrowth after 3–6 months. Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth.

Minoxidil solution and foam are used to help hair growth in the treatment of male pattern baldness. It is not used for baldness at the front of the scalp or receding hairline in men. The foam and 2 percent minoxidil solution is also used to help hair growth in women with thinning hair.

Minoxidil Oral Hypoglycemic Agents CAS 38304-91-5 High Blood Pressure And Hair Loss 1