Sibutramine White Powder Is 99% Hypoglycemic And Lipid-Lowering Raw Material
1, Product title: Sibutramine
Diet pills. Obesity treatment, including weight loss and maintenance of weight loss, should be combined with a low-calorie diet and exercise. It is recommended for the treatment of obese patients with bmi ≥30kg/m2 or ≥27kg/m2(with other risk factors such as hypertension, diabetes, dyslipidemia, etc.).
2, Product parameter table:
Product Name | Sibutramine |
CAS No | 106650-56-0 |
Molecular weight | 279.85 |
Molecular formula | C17H26ClN |
Density | 1.031 g/cm3 |
Boiling point | 342.6 ℃ at 760 mmHg |
Melting point | 191-192℃ |
Point of flammability | 161℃ |
Drug name: Sibutramine
Chemical name :N-{1-[1-(4-chlorophenyl) cyclobutyl] -3-methyl butyl}-N, N' -dimethylamine monohydrate hydrochloride,
Molecular formula: C17H26ClN? HCl? H2O,
Soluble in methanol melting point :193.0~195.0℃
Burning residue :≤0.1%
Heavy metals (Pb) : 10.0 PPM or less
Thin plate chromatography (TLC): Only a single spot
Impurities: 0.2% or less
Total impurities :≤0.4% content :≥99.0%.
Drug alias: Tramex, Olina, nometine Aolina, Reductil
Sibutramine hydrochloride,
Drug description: 10mg: capsule, content is white or quasi-white powder. Tablet :10mg/ tablet.
Body mass index (BMI) calculation: weight (kg) divided by height (m) squared value (kg/m2). The recommended starting dose is 10mg once a day, taken alone or with food in the morning. If weight loss is insufficient, the dose can be adjusted to 15mg per day after 4 weeks. If the patient cannot tolerate a 10mg dose, it may be reduced to 5mg. The dose should be adjusted according to the patient's blood pressure and heart rate. Doses above 15mg/ day are not recommended.
drug
Fold sibutramine
Because xibutramine, fenfluramine and other drugs are cheap, and do have a certain effect of suppressing food to reduce weight, often by a few illegal businessmen cleverly added food to reduce weight for profiteering. Sibutramine has killed dozens of people in Germany, the U.S. and Italy and has been banned in many countries. The expert reminds consumer, below unwitting circumstance took the health care food that contains this composition to reduce weight, produce serious consequence likely. (Some consumers also have some side effects, sibutru name can also make endocrine disorders, have strong side effects on the skin, such as "fire" symptoms! Attention, please!)
SCOUT study(Sibutramine Cardiovascular Outcome Trial)
From December 2002, a large-scale Trial called SCOUT(Sibutramine Cardiovascular Outcome Trial) was initiated. A total of 9,800 obese and overweight people took part in the study. The participants were all over 55 years old and had a history of heart disease and diabetes, but not a recent relapse. The whole experiment lasted for six years.
Comparing the SCOUT group with a placebo group, those taking sibutramine lost an average of only 2 to 4 kilograms more. And it's not clear whether the effect is sustained after the drug is stopped. Sibutramine carries a serious but not fatal risk of cardiovascular disease, such as stroke and heart attack. This research led directly to sibutramine's ban in the European Union