Antibiotics Anti-Inflammatory Josamycin Propionate Raw Steroids Powder

1,  Product title: Josamycin propionate

2,  Product Description:

Crossamycin propionate is commonly used as granules. Antibiotic drugs. This product is suitable for pharyngitis and tonsillitis caused by pyogenic streptococcus, nasal sinusitis, otitis media, acute bronchitis and oral abscess caused by sensitive bacteria, pneumonia caused by mycoplasma pneumoniae, skin and soft tissue infection caused by sensitive bacteria, also can be used for penicillin, erythromycin resistant staphylococcus infection.

3,  Product parameter table:

4,  indications:

This product is suitable for pharyngitis and tonsillitis caused by pyogenic streptococcus, nasal sinusitis, otitis media, acute bronchitis and oral abscess caused by sensitive bacteria, pneumonia caused by mycoplasma pneumoniae, skin and soft tissue infection caused by sensitive bacteria, also can be used for penicillin, erythromycin resistant staphylococcus infection.

5,  Adverse reactions:

1. Gastrointestinal reactions include diarrhea, nausea, vomiting, middle and upper abdominal pain, mouth and tongue pain, gastric hypopnea, etc. The incidence is dose-related. The incidence of gastrointestinal reaction was significantly lower than that of erythromycin.

2, fatigue, nausea, vomiting, abdominal pain, fever and abnormal liver function and other liver toxicity symptoms are rare, jaundice is occasionally seen.

3. Large doses of this product may cause hearing loss, which can mostly be recovered after withdrawal.

4. Occasionally, allergic reactions are seen, including drug fever, rash, and eosinophilia.

5, occasionally have arrhythmia, oral or vaginal candida infection.

6,  Matters needing attention:

1. When the patient is allergic or intolerant to one of the macrolides (such as erythromycin), he/she may also be allergic or intolerant to other macrolides (such as this product).

2. Patients with hemolytic streptococcal infection should be treated with this product for at least 10 days to prevent the occurrence of acute rheumatic fever.

3. Patients with renal dysfunction generally do not need to reduce the dosage.

4. Regular follow-up of liver function should be conducted during the administration of this product. Doses should be appropriately reduced in patients with liver disease and severe renal impairment.

5. Intervention to laboratory inspection indicators: this product can interfere with the fluorescence determination of Higerty method, so that the determination value of urinary catecholamine appears false increase. Serum alkaline phosphatase, bilirubin, alanine aminotransferase and aspartate aminotransferase may be increased.

6, because different bacteria have certain differences in the sensitivity of this product, it is appropriate to make drug sensitivity test.

7,  Pharmacological effects:

1. This product is propionate derivative of crossamycin, a macrolide antibiotic produced by Streptomyces. Its antibacterial spectrum is similar to that of erythromycin, and its antibacterial effect on Staphylococcus and Streptococcus is slightly worse than that of erythromycin, but it still has antibacterial activity on induced drug-resistant strains. Neisseria meningitidis, pertussis bacillus sensitive to this product; It has a good antibacterial effect on anaerobic bacteria such as digestive coccus, digestive streptococcus, propionibacter and true bacillus. Intracellular pathogens such as Mycoplasma, Chlamydia, Legionella are also sensitive to this product.

2. This product does not induce resistance of Staphylococcus to macrolides, and it is a non-inductive antibiotic.

8,  Pictures of the product: