Zhejiang Kanying Import & Export Co. Ltd 86--17169758851 kanyingexport@gmail.com
White Crystalline Ivermectin Powder C48H74O14 Cas 70288-86-7

White Crystalline Ivermectin Powder C48H74O14 Cas 70288-86-7

  • High Light

    White Crystalline Ivermectin Powder

    ,

    cas 70288-86-7

    ,

    Ivermectin Powder C48H74O14

  • Product Name
    Ivermectin
  • Brand Name
    Kan Ying
  • Purity
    99%
  • Shelf Life
    2 Years
  • Storage
    Cool Dry Place
  • Color
    White Crystalline Powder
  • Place Of Origin
    India
  • CAS No
    70288-86-7
  • Boiling Point
    N/A
  • Melting Point
    N/A
  • Place of Origin
    India
  • Brand Name
    Kan Ying
  • Minimum Order Quantity
    1kg
  • Price
    To discuss
  • Packaging Details
    1kg-25kg
  • Delivery Time
    2
  • Payment Terms
    L/C, D/A, D/P, T/T, Western Union, MoneyGram,Dollars
  • Supply Ability
    200000

White Crystalline Ivermectin Powder C48H74O14 Cas 70288-86-7

Ivermectin Antibiotic antiparasitic drugs White crystalline powder

 

1. Product title: Ivermectin


2. Product parameter table:

Product Name

Ivermectin

Specification 99%
Appearance White crystalline powder Main Effect Antibiotic antiparasitic drugs
Brand Name Kan Ying Store-method Cool Dry Place
Shelf Life 2 Years When
Properly Stored
From India

 
3. Product introduction:Ivermectin is a new type of broad-spectrum, high-efficiency, low-toxic antibiotic antiparasitic drug, which has a good repellent effect on internal and external parasites, especially nematodes and arthropods. But it has no effect on tapeworms, flukes and protozoa. The repellent effect of macrolide antiparasitic drugs on nematodes and arthropods is to increase the release of the inhibitory transmitter γ-aminobutyric acid (GABA) and to open the Cl ion channel controlled by glutamate. Enhance the permeability of the nerve membrane to Cl, thereby blocking the transmission of nerve signals, and eventually nerve paralysis, causing muscle cells to lose the ability to contract, which leads to the death of the worm.


4. Ivermectin physicochemical properties:

Molecular formula C48H74O14
Molecular weight 875.09300
Accurate quality 874.50800
PSA 170.06000
LogP 5.60140
Appearance: white to off-white solid
Storage conditions
Store in an airtight container in a cool, dry place. Store away from oxidizing agents.
 
Store at 2-8 ºC.
 
Stability
Keep away from heat, open flames and sparks.
 
Water solubility H2O: ≤1.0% KF
Molecular Structure
1. Molar refractive index: 230.72
 
2. Molar volume (cm3/mol): 708.3
 
3. Isotonic specific volume (90.2K): 1901.5
 
4. Surface tension (dyne/cm): 51.9
 
5. Polarizability (10-24cm3): 91.46
 
Computational Chemistry
1. Hydrophobic parameter calculation reference value (XlogP):
 
2. Number of hydrogen bond donors: 6
 
3. Number of hydrogen bond acceptors: 28
 
4. Number of rotatable chemical bonds: 15
 
5. Topological molecular polar surface area (TPSA): 340
 
6. Number of heavy atoms: 123
 
7. Surface charge: 0
 
8. Complexity: 3340
 
9. Number of isotope atoms: 0
 
10. Determine the number of atomic stereo centers: 38
 
11. Uncertain number of atomic stereo centers: 1
 
12. Determine the number of chemical bond stereo centers: 6
 
13. Uncertain the number of chemical bond stereo centers: 0
 
14. Number of covalent bond units: 2
 
More
1. Properties: off-white crystalline powder.
 
2. Density (g/mL, 25/4℃): Not determined
 
3. Relative vapor density (g/mL, air=1): not determined
 
4. Melting point (ºC): not determined
 
5. Boiling point (ºC, normal pressure): not determined
 
6. Boiling point (ºC, 5.2kPa): not determined
 
7. Refractive index: not determined
 
8. Flash point (ºC): not determined
 
9. Specific rotation (º): not determined
 
10. Auto-ignition point or ignition temperature (ºC): not determined
 
11. Vapor pressure (kPa, 25ºC): not determined
 
12. Saturated vapor pressure (kPa, 60ºC): not determined
 
13. Heat of combustion (KJ/mol): not determined
 
14. Critical temperature (ºC): not determined
 
15. Critical pressure (KPa): not determined
 
16. The logarithm of the partition coefficient of oil and water (octanol/water): not determined
 
17. Upper explosion limit (%, V/V): not determined
 
18. Lower explosion limit (%,V/V): not determined
 
19. Solubility: soluble in methanol, esters and aromatic hydrocarbons, but insoluble in water.

 
5. Precautions:Relevant historical data indicate that antifilarial drugs [such as diethylamine citrate (DEC-C)] can cause severe allergic reactions (Mazzotti reactions) and ophthalmological reactions in patients with onchocercia microfilament larvae. . These reactions may be due to allergic and inflammatory reactions caused by dead microfilament corpses. These reactions may occur clinically in patients with onchocerciae larvae treated with ivermectin, which may or definitely be related to the drug itself. After treatment with microfilariasis drugs, patients with allergic onchocercia dermatitis are more likely to have serious adverse reactions, especially edema and onchocercia dermatitis aggravate carcinogenicity, mutagenicity and reproductive toxicity. When using this product, patients with strongyloidiasis must repeat the fecal examination to make sure that the strongyloidiasis infection has been cleared. This product cannot kill the adults of Onchocerciasis, so when using this product to treat onchocerciasis, continuous treatment is required. Strongyloidiasis in immunodeficiency hosts: Patients with immunodeficiency (including HIV infection) may require repeated treatment for intestinal strongyloidiasis. For these patients, clinical trials have not been conducted to determine the alternative dosage regimen, and suppressive therapy (such as once a month) may be effective.

 

6.  Product pictures :

White Crystalline Ivermectin Powder C48H74O14 Cas 70288-86-7 0White Crystalline Ivermectin Powder C48H74O14 Cas 70288-86-7 1