Coenzyme Q10 Conducive To Anti-Heart Failure Treatment Yellow To Orange Yellow Crystalline Powder

1. Product title: coenzyme Q10
2. Product parameter table:

 
3. Product introduction:Coenzyme Q10, the chemical name is 2-[(全-E) 3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22, 26,30,34,38-Tetradecenyl}-5,6-dimethoxy-3-methyl-p-benzoquinone, [1] is the electron transport chain and aerobic respiration in the mitochondria of eukaryotic cells One of the participating substances is yellow to orange-yellow crystalline powder, odorless and tasteless, easy to decompose when exposed to light.
4. Chemical and physical properties of coenzyme Q10:

 
5. In vivo research: Due to its hydrophobicity and large molecular weight, the absorption of dietary coenzyme Q10 is slow and limited. In the case of dietary supplements, the solubilized coenzyme Q10 formulation showed enhanced bioavailability. Tmax is about 6 hours, and the elimination half-life is about 33 hours. The reference interval of plasma coenzyme Q10 is 0.40-1.91mM in healthy subjects. With coenzyme Q10 supplements, there is a reasonable correlation between the increase in plasma coenzyme Q10 and the intake dose, up to a certain point. Animal data show that large doses of coenzyme Q10 are taken up by all tissues including heart and brain mitochondria [2]. In 12-month-old rats, administration of coenzyme Q10 resulted in a significant increase in the concentration of coenzyme Q10 in the mitochondria of the cerebral cortex. Oral administration of coenzyme Q10 significantly reduced the striatal lesions caused by systemic administration of 3-nitropropionic acid, and significantly prolonged the life of the transgenic mouse model of familial amyotrophic lateral sclerosis [3].
 

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