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Weight Loss Raw Material Sibutramine CAS106650-56-0 Quality Assurance

Weight Loss Raw Material Sibutramine CAS106650-56-0 Quality Assurance

  • Product Title
    Sibutramine
  • Brand Name
    Kan Ying
  • Purity
    99%
  • Color
    White Granules Or Powder
  • CAS No
    106650-56-0
  • Boiling Point
    342.6℃ At 760 MmHg
  • Melting Point
    191-192℃
  • Flash Point
    161℃
  • Shelf Life
    2 Years
  • Storage
    Cool Dry Place
  • Place of Origin
    India
  • Brand Name
    Kan Ying
  • Minimum Order Quantity
    1kg
  • Price
    To discuss
  • Packaging Details
    1kg-25kg
  • Delivery Time
    2
  • Payment Terms
    L/C, D/A, D/P, T/T, Western Union, MoneyGram,Dollars
  • Supply Ability
    200000

Weight Loss Raw Material Sibutramine CAS106650-56-0 Quality Assurance

1. Product title:Sibutramine

 

2. Product parameter table:

 

Product Name Sibutramine Specification 99%
Appearance White granules or powder Main Effect Raw materials for weight loss
Brand Name Kan Ying Store-method Cool Dry Place
Shelf Life 2 Years When
Properly Stored
From India

 

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Weight loss raw materials sibutramine market price foreign manufacturers direct sales API Sibutramine

[Usage and Dosage] The dosage of Western Quming is reported to be 50~55 mg, and we suggest 55~60 mg for Oriental people. Compared with citric acid, western tramine has the advantages of small amount of addition, very small side effects, and slightly soluble in water and ethanol.

The recommended dosage is 50mg once a day, alone in the morning or with breakfast. If weight loss is not significant, the dose can be increased to 55mg/day after 4 weeks, or reduced to 5mg/ day if the patient cannot tolerate 50mg/ day. Doses above 55mg/ day are not recommended.

[Time of effect] After taking Western Tramine, it is absorbed through the intestines and stomach, about 50%** in 30 minutes, 83% ** in 1 hour, the effect lasts for 8-12 hours, the half-life of adults is 40-116 hours, and the half-life is prolonged when the nerve function is not complete.

Weight loss raw materials sibutramine market price foreign manufacturers direct sales API Sibutramine

 

Summary of Sibutramine (106650-56-0) :


An inhibitor of central nervous system with excitatory and inhibitory effects, it may cause serious side effects such as elevated blood pressure, accelerated heart rate, anorexia, insomnia and abnormal liver function. Because xibutramine, fenfluramine and other drugs are cheap, and do have a certain effect of suppressing food to reduce weight, often by a few illegal businessmen cleverly added food to reduce weight for profiteering. Sibutramine has killed dozens of people in Germany, the U.S. and Italy and has been banned in many countries. The expert reminds consumer, below unwitting circumstance took the health care food that contains this composition to reduce weight, produce serious consequence likely.

 

Notes for Sibutramine (106650-56-0) :


Contraindicated in patients receiving monoamine oxidase inhibitors (MAOI). Contraindicated in patients allergic to this ingredient.

Contraindicated in patients with anorexia nervosa. Contraindicated in patients receiving other central appetite suppressants. The treatment of glutenia should be based on diet control and exercise. Organic obesity (e.g., untreated hypothyroidism) should be excluded. Blood pressure and pulse should be checked before treatment and monitored regularly during treatment. Consider reducing or discontinuing the drug in those with persistent elevated blood pressure and pulse. Patients with a history of hypertension should be carefully used, blood pressure can not be controlled or poorly controlled patients with hypertension should be prohibited.

Certain central weight-loss drugs that cause the release of serotonin from nerve endings have been associated with heart valve insufficiency because of the potential for increased heart rate and/or increased blood pressure. Two foreign studies have been carried out on the possibility of heart valve disease: In a study of 210 patients (mean age 54 years) who received sibutridine hydrochloride or placebo 15mg daily for up to 2 weeks to 16 months and had no history of valvular heart disease, the incidence of valvular heart disease was 3/132(2.3%) in the sibutridine hydrochloride group. All three cases had mild aortic insufficiency, compared with 2/77(2.6%) in the placebo group, with one mild aortic insufficiency and one severe aortic insufficiency. In another study, no heart valve disease was observed in 25 patients treated with sibutramine hydrochloride 5 to 30mg daily for 3 months using 2 and color doppler echocardiography. Certain central weight-loss drugs that cause the release of serotonin from nerve endings can induce pulmonary hypertension (PPH), a rare but fatal condition.

No similar cases have been found in the clinical study of this product before marketing, but it is not certain whether this product can cause this disease due to the low incidence of this disease in the population. Patients with severe hepatic or renal insufficiency should not take this product. Since weight loss can increase and aggravate the formation of gallstones, patients suffering from gallstones should use this product with caution.

This product can cause pupil dilation, so it is used in patients with angle-closure glaucoma. Use with caution in patients with a history of epilepsy. Discontinue use in patients with epileptic seizures. Although sibutramine hydrochloride did not affect psychomotor and thought behavior in healthy volunteers, any drug that acts on the central nervous system has the potential to affect judgment, thinking, or motor skills. Teratogenic effect of sibutramine hydrochloride was observed in animal tests, but carcinogenic and mutagenic effect was not observed. It is recommended that women who are pregnant, preparing for pregnancy and lactation should not take this product.

Sibutramine hydrochloride is not recommended for children under 16 years of age because the safety and efficacy of sibutramine hydrochloride in children under 16 years of age has not been established. Due to reduced cardiac, kidney, and liver function or the increased likelihood of treatment for other diseases, the elderly should be carefully selected for dosage.

 
7. Pictures of the product:
 
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