C28H44O Vitamin D2 Avanafil Powder Regulating Immune Chronic Hypocalcemia

Vitamin D2 Regulating Immune Function Avanafil Powder Chronic Hypocalcemia

1. Product title: Vitamin D2

2. Product Description: Vitamin D2(Vitamin D2), chemically known as 9, 10-open-ring ergosteroid-5, 7, 10 (19), 22-tetraene-3β-alcohol. Colorless needle-like crystal or white crystalline powder; Odorless, tasteless; Both light and air are perishable. For the prevention and treatment of vitamin D deficiency, chronic hypocalcemia, low phosphorus, rickets and osteomalacia associated with chronic renal insufficiency, familial low phosphorus and low parathyroid function (postoperative parathyroid function), idiopathic or sham treatment, used in the treatment of acute and chronic and potential tetany disease and idiopathic tetany after surgery.

3.Product parameter table:

4. Pharmacology and toxicology:

This product is a vitamin medicine. Vitamin D2 promotes the absorption of calcium in the brush margin of small intestine mucosa and the reabsorption of phosphorus in renal tubules, increases the concentration of blood calcium and phosphorus, and promotes the release of calcium phosphate from old bone with the coordination of parathyroid hormone (PTH) and calcitonin (CT), and maintains and regulates the normal concentration of plasma calcium and phosphorus. Vitamin D2 promotes calcium deposition at the site of new bone formation, deposition of citrate in bone, promotion of bone calcification, function of osteoblasts and maturation of bone-like tissues. After vitamin D2 is ingested, calcitriol (25-OHD3) is catalyzed by 25-hydroxylase system in cellular microsomes, and calcitriol (1-25-(OH)2D3) with biological activity is produced by 1-hydroxylase system in renal adjacent convolute cells. In animal experiments, after parathyroid gland excision in mice, 1-hydroxylase activity was lost and calcitriol synthesis could not be achieved. In hypercalcemia, CT secretion increased and 1-hydroxylase activity was inhibited, which reduced the conversion of calcitriol into calcitriol. It was confirmed that calcitriol metabolism was regulated by PTH and CT, and phosphate and calcium could also regulate 1-hydroxylase activity.

5. ndications:

1. For the prevention and treatment of vitamin D deficiency. Such as: vegan, parenteral nutrition

Compound zinc vitamin D calcium

Compound zinc vitamin D calcium

Patients, pancreatic insufficiency with malabsorption syndrome, hepatobiliary diseases (liver damage, cirrhosis, obstructive jaundice), small intestinal diseases (fatty diarrhea, localized enteritis, long-term diarrhea), gastrecision, etc.

6. Pictures of the product: