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Parasitic Resistance Cas 63968-64-9 Artemisinin Powder Regulating Immune

Parasitic Resistance Cas 63968-64-9 Artemisinin Powder Regulating Immune

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    Parasitic Resistance Artemisinin Powder

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    Cas 63968-64-9 Artemisinin Powder

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    Cas 63968-64-9

  • Product Name
    Artemisinin
  • Brand Name
    Kan Ying
  • Purity
    99%
  • Place Of Origin
    India
  • Storage
    Cool Dry Place
  • CAS No
    63968-64-9
  • The Molecular Weight
    282.4
  • Boiling Point
    389.9±42.0 °C At 760 MmHg
  • Melting Point
    156-157ºC
  • Point Of Flammability
    172.0±27.9 °C
  • Place of Origin
    India
  • Brand Name
    Kan Ying
  • Minimum Order Quantity
    1kg
  • Price
    To discuss
  • Packaging Details
    1kg-25kg
  • Delivery Time
    2
  • Payment Terms
    L/C, D/A, D/P, T/T, Western Union, MoneyGram,Dollars
  • Supply Ability
    200000

Parasitic Resistance Cas 63968-64-9 Artemisinin Powder Regulating Immune

Artemisinin Regulating immune function Regulating immune function

 

1,  Product title:   Artemisinin 

 

2,  Product Description:

 

Artemisinin is a sesquiterpenoid lactone drug with peroxy group extracted from the stem and leaves of Artemisia annua. The effect of the drug on the ultrastructure of rat plasmodium in red phase is mainly the change of plasmodium membrane structure. The drug first acts on food vesicle, membrane, mitochondria and endoplasmic reticulum, and also has some effect on nuclear chromatin. It is suggested that artemisinin interferes with the function of mitochondria. It may be that artemisinin acts on the food vesicle, thus blocking the earliest stage of nutrient intake, causing the malaria parasite to quickly starve of amino acids, rapidly form autophagy vesicles, and continuously expel the parasite, causing the malaria parasite to lose a large number of cytoplasm and die. The uptake of tritium-labeled isoleucine by P. falciparum cultured in vitro also suggested that its initial action might be inhibition of protozoan protein synthesis.青蒿素是从植物黄花蒿茎叶中提取的有过氧

 

3,  Product parameter table:

 

 

Product Name Artemisinin Specification 99%
Appearance White or light white power Main Effect Parasitic resistance
Brand Name Kan Ying Store-method Cool Dry Place
Shelf Life 2 Years When
Properly Stored
From India

 

 

4,  In vivo studies:

 

Artemisinin (50,100 or 200mg/kg B.t/day, Po) prevents isoflurane-induced impairment of working memory, as observed in the T-maze test. Artemisinin enhances spatial navigation and memory in isoflurane exposed rats. Rats treated with artemisinin showed significantly better performance than those treated with isoflurane alone.

 

5,  Description of necessary first aid measures:


The suction
If inhaled, remove victim to fresh air. If breathing has stopped, give artificial respiration.
Skin contact
Rinse with soap and plenty of water.
Eye contact
Flush eyes with water as a precaution.
eat
Never feed anything through the mouth to an unconscious person. Rinse your mouth with water.

 

6,  Pharmacological effects:


1. Artemisinin is a sesquiterpene lactone drug with peroxygen group extracted from Artemisia annua, a traditional Chinese medicine. It is a highly effective, quick - acting, low - toxicity antimalarial drug. It has a strong and rapid killing effect on Plasmodium erythrocyte phase, and can quickly control the clinical outbreak and symptoms.

 

2. The mechanism of artemisinin is still not clear. It mainly interferes with the mitochondrial function of plasmodium. Artemisia annua Qin changes the membrane structure of Plasmodium by affecting the ultrastructure of the erythrocyte phase. Due to the action of food vesicle, the nutrient intake of Plasmodium is blocked. When the Plasmodium loses a large amount of cytoplasm and nutrients, and cannot be replenished, it soon dies.

 

3. Its mode of action is to produce unstable organic free radicals and/or other electronophilic intermediaries through the internal peroxide (dioxygen) bridge mediated by the free iron produced after the decomposition of hemoglobin, and then form covalent admixture with the plasmodium protein, causing the plasmodium to die. The antimalarial activity of artemether is 6 times greater than that of artemisinin.

 

7,  pharmacokinetics:


After absorption, the product is distributed in the tissue, with more intestinal, liver and kidney content. This product is a fat soluble substance that can easily penetrate the blood-brain barrier into the brain tissue. Fast metabolism in the body, mainly from the kidney and intestinal tract excretion, 24 hours can be excreted 84%, 72 hours only a small amount of residual. Due to the rapid metabolism and excretion, and the short maintenance time of effective blood drug concentration, it is not conducive to the complete killing of Plasmodium, so the reburning rate is high.

 

 

8,  Pictures of the product:

 

Parasitic Resistance Cas 63968-64-9 Artemisinin Powder Regulating Immune 0Parasitic Resistance Cas 63968-64-9 Artemisinin Powder Regulating Immune 1